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Reimagine Aging
PNAS
PNAS


Molecular characterization of latent GDF8 reveals mechanisms of activation.

Walker RG,...,Lee RT et al. PNAS, 2018. 

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Key PublicationsSharon R. ReavesOctober 20, 2017Our Publications, History
Journal of Alzheimer's Disease
Journal of Alzheimer's Disease

GDF11 Rejuvenates Cerebrovascular Structure and Function in an Animal Model of Alzheimer’s Disease. 

Zhang et al. Journal of Alzheimer’s Disease, 2018.

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Key PublicationsSharon R. ReavesOctober 19, 2017Other Relevant Publications, Brain
Science Direct
Science Direct

GDF11 improves neurobehavioral recovery and stimulates angiogenesis in rats subjected to cerebral ischemia/reperfusion.

Ma et al., Brain Research, 2018.

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Key PublicationsSharon R. ReavesOctober 15, 2017Brain
Journal of Clinical Neuroscience
Journal of Clinical Neuroscience

Neuroprotective potential of GDF11 in experimental intracerebral hemorrhage in elderly rats.

Xiao et. al. Journal of Clinical Neuroscience, 2019.

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Key PublicationsSharon R. ReavesOctober 11, 2017Metabolic Disease
Frontiers In Cellular Neuroscience
Frontiers In Cellular Neuroscience

GDF11 Promotes Neurovascular Recovery After Stroke in Mice

Xiao et al. J. Clinical Neuroscience, 2019.

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Key PublicationsSharon R. ReavesOctober 10, 2017Brain
American Diabetes Association
American Diabetes Association

GDF11 Improves Angiogenic Function of EPCs in Diabetic Limb Ischemia.

Zhang et al. Diabetes, 2018.

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Key PublicationsSharon R. ReavesSeptember 1, 2017Metabolic Disease
Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology.
Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology.


Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology.

Idkowiak-Baldys J,…, Rubin LL. PLoS ONE, 2019.

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Key PublicationsSharon R. ReavesAugust 23, 2017
Aging Cell, Wiley Online Libaray
Aging Cell, Wiley Online Libaray

Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction-like phenotype in aged mice.

Katsimpardi et al. Aging Cell, 2019.

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Key PublicationsSharon R. ReavesAugust 22, 2017Metabolic Disease
Gut
Gut

Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells

Dai et al., Gut, 2019.

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Key PublicationsSharon R. ReavesJuly 22, 2017
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice. 
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice. 

Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice.

Walker, RG,…, Wagers AJ, Lee RT. Sci Rep, 2020.

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Key PublicationsSharon R. ReavesJuly 22, 2016Metabolic Disease
Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice
Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice

Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice

Hudobenko et al. Aging, 2020.

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Key PublicationsSharon R. ReavesJuly 21, 2016Brain
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