Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy.

Loffredo FS,...,Wagers AJ, Lee RT. Cell, 2013.

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle.

Sinha M,...,Lee RT, Wagers AJ. Science, 2014. 

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors.

Katsimpardi L,...,Lee RT, Wagers AJ, Rubin LL. Science, 2014. 

Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans.

Olson KA et al. European Heart Journal, 2015.

Biochemistry and Biology of GDF11 and Myostatin Similarities, Differences, and Questions for Future Investigation. 

Walker RG,...,Rubin LL, Wagers AJ, Lee RT. Circulation Research, 2016. 

Structural basis for potency differences between GDF8 and GDF11.

Walker RG,...,Wagers AJ, Lee RT et al. BMC Biology, 2017.

Molecular characterization of latent GDF8 reveals mechanisms of activation.

Walker RG,...,Lee RT et al. PNAS, 2018.